ABSTRACT
ABSTRACT One patient with a history of trabeculectomy with Mitomicin C 0.02%, but no history of systemic disorders, exhibited unilateral corneal lipid infiltrates, together with deep stromal vascularization. She was treated with a bevacizumab injection and penetrating keratoplasty. No sign of recurrence was noted after one year post-operative.
RESUMO Um paciente com história de trabeculectomia com Mitomicina C 0,02%, sem doenças sistêmicas pré-existentes, apresentou infiltrado lipídico corneano unilateral associado à vascularização intraestromal profunda. Injeção subconjuntival de Bevacizumabe foi realizada e posterior ceratoplastia penetrante. Não houve sinais de recorrência em um ano.
Subject(s)
Humans , Female , Middle Aged , Bevacizumab/therapeutic use , Cornea/metabolism , Keratoplasty, Penetrating , Mitomycin , Phospholipids/metabolism , TrabeculectomyABSTRACT
The purpose of the authors is to show clinical findings of a patient with benign concentric annular macular dystrophy, which is an unusual condition, and part of the bulls eye maculopathy differential diagnosis. An ophthalmologic examination with color perception, fluorescein angiography, and ocular electrophysiology was performed.
O objetivo dos autores é detalhar o quadro clínico de um paciente com distrofia macular anular concêntrica benigna, quadro raro, que compõe o diagnóstico diferencial das maculopatias em alvo. Realizou-se avaliação oftalmológica com auxílio de testes de percepção de cores, angiofluoresceinografia e eletrofisiologia ocular.
Subject(s)
Humans , Male , Adult , Color Perception , Retinal Diseases/diagnosis , Electrophysiology , Fluorescein Angiography , Macula Lutea/pathology , Diagnosis, DifferentialABSTRACT
Host use by vectors is important in understanding the transmission of zoonotic diseases, which can affect humans, wildlife and domestic animals. Here, a synthesis of host exploitation patterns by kissing-bugs, vectors of Chagas disease, is presented. For this synthesis, an extensive literature review restricted to feeding sources analysed by precipitin tests was conducted. Modern tools from community ecology and multivariate statistics were used to determine patterns of segregation in host use. Rather than innate preferences for host species, host use by kissing-bugs is influenced by the habitats they colonise. One of the major limitations of studies on kissing-bug foraging has been the exclusive focus on the dominant vector species. We propose that expanding foraging studies to consider the community of vectors will substantially increase the understanding of Chagas disease transmission ecology. Our results indicate that host accessibility is a major factor that shapes the blood-foraging patterns of kissing-bugs. Therefore, from an applied perspective, measures that are directed at disrupting the contact between humans and kissing-bugs, such as housing improvement, are among the most desirable strategies for Chagas disease control.
Subject(s)
Animals , Ecosystem , Feeding Behavior/physiology , Insect Vectors , Insect Vectors/physiology , Triatominae , Triatominae/physiology , Birds/blood , Mammals/bloodABSTRACT
Phlebotomine sand flies (Diptera: Psychodidae: Phlebotominae) are vectors of Leishmania parasites, etiological agents of leishmaniases in humans and other mammals worldwide. A previous study showed that at large biogeographical scales sand fly patterns of co-occurrence are segregated, indicating that sand fly communities at such scales are likely shaped by environmental factors and inter-specific interactions. However, no study has addressed co-occurrence patterns at the local scale of disease transmission. Here, a null-model analysis of species co-occurrence patterns is presented, showing that at the local scale patterns of sand fly species co-occurrence shift from a segregated structure to random when comparing a forest to a farmland. These patterns may explain the ecological fitting of sand flies with regard to the choice of diurnal resting sites in transformed landscapes, which may impact the transmission of Leishmania parasites by disrupting patterns of blood foraging across vertebrate hosts.
Los flebotómos (Diptera: Psychodidae: Phlebotominae) son vectores de los parásitos Leishmania, agentes etiológicos de las leishmaniasis en el ser humano y otras especies de mamíferos a nivel mundial. Investigaciones previas demostraron que en escalas regionales las especies de angoletas se segregan, posiblemente por la influencia de factores ambientales e interacciones inter-específicas. Sin embargo, los patrones de co-ocurrencia no han sido estudiados a nivel local. Aquí se presenta un análisis de modelos nulos de patrones de co-ocurrencia que muestra que los patrones de co-ocurrencia de especies de flebotómos pasan de segregados a agregados cuando se compara un bosque con una granja. Tal resultado podría explicarse en el ajuste ecológico de los flebotómos con respecto a la selección de sitios de descanso diurno en paisajes transformados. Este ajuste ecológico podría impactar la transmisión de los parásitos de Leishmania al cambiar los patrones de alimentación sanguínea de los flebotómos con respecto a varias especies de hospedadores vertebrados.
ABSTRACT
Se estudió la mortalidad de 48 hembras adultas de Rhodnius robustus. Dada la significancia estadística del ajuste de los datos al modelo de Gompertz (p<0.0001), se puede afirmar que el mismo permite describir la mortalidad de esta especie.